About methemoglobinemia.

I would like to add to this well written article that we have also reported acquired methemoglobinemia cases with administration of cytanest in puerperal women with g6PD deficiency and infants in whom erythrocyte cytochrome 65 reductase was assoyed [1-4], which is the main enzyme for methemoglobin reductase in erythrocytes as mentioned by the authors. In addition, hereditary methemoglobinemias due to nADH dependent cytochrome reductase (nADH dependent methemoglobine reductase = nADH dependent diaphorase) deficiency, which was assayed only by us so far in Turkey with probable dominant inheritance and Hemoglobin m cases were reported on several journals [5-11].